"As a Japanese creator, I want to make something that only Japanese people can make. I don't want to follow the European people's way," he told Gamasutra in a new feature interview. While his studio is based in Japan, parent Ignition Entertainment is headquartered in the UK.1 Enoch is part of the Old Testament pseudepigrapha, although, given its transmission and use in Christian circles, it could be regarded as a Christian apocryphon as well. It is canonical only to the Ethiopic Church, so it outside the biblical canon not only for Protestants, but also Jews, Catholics and the (Christian) Orthodox.
The game is based books from the Christian Apocrypha, books considered by Protestant Christians to not be part of the Biblical canon. El Shaddai is essentially a Japanese imagining of parts of the Western religion. The main character in the game is Enoch, a very pure former human that is now working for God.
"I read, of course, the Book of Enoch, and I also read a lot of other people's books dealing with those two characters. I think all of those books were boring," said Sawaki, who also worked at Capcom on Devil May Cry and Okami. "I think my image of Enoch is closer to the original Enoch. Because I read a lot of information, and based on that, I drew this Enoch."
Background here.