Monday, December 17, 2012

Samaritans and genetic testing

TECHNOLOGY WATCH:
Samaritans, an ancient sect, find new hope with genetic testing

By Edmund Sanders
Los Angeles Times


MOUNT GERIZIM, West Bank — When Ben Yehuda Altif got engaged to his first cousin Mazal, there was no problem winning the blessing of their families or the Samaritan high priest, who leads their ancient Israelite sect. Marriage between cousins is common in the religious community.

But there was still an obstacle. Like many Samaritan couples today, the pair had to pass a premarital genetic screening to predict the likelihood of having healthy children. Without the green light from doctors, the marriage would be off.

"Doctors said OK, and now we have a healthy, handsome boy," said Altif, 33, reaching for his wife's cellphone to show off pictures of their son.

Samaritans, who trace their roots back about 2,700 years, are best known for clinging to strict biblical traditions that have largely disappeared, including animal sacrifice, isolation of menstruating women and, until recently, a ban on marrying outsiders.

But after facing near-extinction and being devastated by a high rate of birth defects because of inbreeding, the community is using modern science — including genetic testing, in vitro fertilization and abortion — to preserve their way of life.

[...]

Over the last decade, the community also relaxed its restrictions on intermarriage, allowing in about 25 women, mostly Jewish Israelis and arranged matches with brides from Ukraine.

Samaritan leaders are reluctant to discuss their gene-pool shrinkage, but they estimate the rate of birth defects was once 10 times higher than the nationwide average.

But since adopting genetic testing, Samaritans say, the rate of birth defects among newborns today is normal, even though most people still marry inside the community, including to relatives.

[...]
This is a positive set of developments, at least for the short term. In the long term, increasing the genetic diversity of the community will become increasingly important, genetic screening or not.

Some past posts dealing with genetic issues for the Samaritans are here, here, here, and here.